Article
Potential Diagnosis of Vitreoretinal Lymphoma by Detection of MYD88 Mutation in Aqueous Humor With Ultrasensitive Droplet Digital Polymerase Chain Reaction.
JAMA ophthalmology - 1 Oct 2018
Hiemcke-Jiwa Laura S, Ten Dam-van Loon Ninette H, Leguit Roos J, Nierkens Stefan, Ossewaarde-van Norel Jeannette, de Boer Joke H, Roholl Floor F, de Weger Roel A, Huibers Manon M H, de Groot-Mijnes Jolanda D F, Kuiper Jonas J W
Abstract excerpt
Importance: The diagnostic workup of patients suspected of having vitreoretinal lymphoma (VRL) is primarily based on vitreous fluid analysis, including the recently emerging myeloid differentiation primary response gene 88 (MYD88) mutation analysis. Aqueous humor paracentesis is a relatively less invasive and safer procedure than taking vitreous fluid specimens, and aqueous humor-based MYD88 mutation analysis...
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