Article
Expression network analysis reveals cord blood vitamin D-associated genes affecting risk of early life wheeze.
Thorax - 1 Feb 2019
Mirzakhani Hooman, Al-Garawi Amal A, Carey Vincent J, Qiu Weiliang, Litonjua Augusto A, Weiss Scott T
Abstract excerpt
Cord blood 25-hydroxyvitamin D (25OHD) has been reported in association with risk of early life recurrent wheeze. In a subset of infants who participated in the Vitamin D Antenatal Asthma Reduction Trial, we demonstrated that higher cord blood 25OHD at birth (>31 ng/mL) was associated with a reduced risk of recurrent wheeze in the first year of life. We then identified a module of co-expressed genes associated...
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