Article
Vitamin D related genes in lung development and asthma pathogenesis.
BMC medical genomics - 5 Nov 2013
Kho Alvin T, Sharma Sunita, Qiu Weiliang, Gaedigk Roger, Klanderman Barbara, Niu Simin, Anderson Chris, Leeder James S, Weiss Scott T, Tantisira Kelan G
Abstract excerpt
BACKGROUND: Poor maternal vitamin D intake is a risk factor for subsequent childhood asthma, suggesting that in utero changes related to vitamin D responsive genes might play a crucial role in later disease susceptibility. We hypothesized that vitamin D pathway genes are developmentally active in the fetal lung and that these developmental genes would be associated with asthma susceptibility and regulation in...
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