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Article

Identification of a key gene module associated with glucocorticoid- induced derangement in bone mineral density in patients with asthma.

Scientific reports - 27 Dec 2019

Lee Suh-Young, Won Ha-Kyeong, Kim Byung-Keun, Kim Sae-Hoon, Chang Yoon-Seok, Cho Sang-Heon, Kelly H William, Tantisira Kelan G, Park Heung-Woo

Abstract excerpt

Derangement in bone mineral density (BMD) caused by glucocorticoid is well-known. The present study aimed to find key biological pathways associated with low BMD after glucocorticoid treatment in asthmatics using gene expression profiles of peripheral blood cells. We utilized immortalized B cells (IBCs) from 32 childhood asthmatics after multiple oral glucocorticoid bursts and peripheral blood mononuclear cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31882850
DOI: 10.1038/s41598-019-56656-9
PMCID: PMC6934743

Genes

CREBBP
EP300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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