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Article

Aldosterone Suppression by Dexamethasone in Patients With KCNJ5-Mutated Aldosterone-Producing Adenoma.

The Journal of clinical endocrinology and metabolism - 1 Sept 2018

Inoue Kosuke, Yamazaki Yuto, Kitamoto Takumi, Hirose Rei, Saito Jun, Omura Masao, Sasano Hironobu, Nishikawa Tetsuo

Abstract excerpt

Context: Aldosterone biosynthesis is regulated principally by ACTH and gene mutations as well as by angiotensin II and serum potassium. In addition, previous studies have reported the potential effects of KCNJ5 mutations in aldosterone-producing adenoma (APA) on cardiovascular diseases. However, responsiveness to ACTH in APAs according to potassium inwardly rectifying channel, subfamily J, member 5 (KCNJ5)...

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Share to Adrenal Cortex Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30020487
DOI: 10.1210/jc.2018-00738

Genes

KCNJ5
DST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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