Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strength in diversity: Understanding the pathways to herpes simplex virus reactivation

15 Jul 2018

Abstract excerpt

Herpes simplex virus (HSV) establishes a latent infection in peripheral neurons and can periodically reactivate to cause disease. Reactivation can be triggered by a variety of stimuli that activate different cellular processes to result in increased HSV lytic gene expression and production of infectious virus. The use of model systems has contributed significantly to our understanding of how reactivation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to Pharmacological Effects of Natural Compounds
Share to Toxin Mechanisms and Immunotoxins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30014861
DOI: 10.1016/j.virol.2018.07.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strength in diversity: Understanding the pathways to herpes simplex virus reactivationPMID 30014861Read ↗

Herpes Simplex Virus Establishment, Maintenance, and Reactivation: In Vitro Modeling of LatencySemantic proximity Read ↗

Mechanisms of HSV gene regulation during latency and reactivationSemantic proximity Read ↗

DLK-dependent biphasic reactivation of herpes simplex virus latency established in the absence of antiviralsSemantic proximity Read ↗

Restarting Lytic Gene Transcription at the Onset of Herpes Simplex Virus ReactivationSemantic proximity Read ↗

Ex Vivo Herpes Simplex Virus Reactivation Involves a Dual Leucine Zipper Kinase-Dependent Wave of Lytic Gene Expression That Is Independent of Histone Demethylase Activity and Viral Genome SynthesisSemantic proximity Read ↗

Ocular Herpes Simplex Virus: How are Latency, Reactivation, Recurrent Disease and Therapy Interrelated?Semantic proximity Read ↗

Co-option of mitochondrial nucleic acid sensing pathways by HSV-1 UL12.5 for reactivation from latent InfectionSemantic proximity Read ↗

Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived NeuronsSemantic proximity Read ↗

Herpes Simplex Virus Evasion of Early Host Antiviral ResponsesSemantic proximity Read ↗

Herpes simplex virus infects most cell types in vitro: clues to its successSemantic proximity Read ↗

HSV Replication: Triggering and Repressing STING FunctionalitySemantic proximity Read ↗

Alphaherpesvirus Latency and Reactivation with a Focus on Herpes Simplex VirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.