HSV Replication: Triggering and Repressing STING Functionality

doi:10.3390/v15010226

Article

HSV Replication: Triggering and Repressing STING Functionality

13 Jan 2023

Abstract excerpt

Herpes simplex virus (HSV) has persisted within human populations due to its ability to establish both lytic and latent infection. Given this, human hosts have evolved numerous immune responses to protect against HSV infection. Critical in this defense against HSV, the host protein stimulator of interferon genes (STING) functions as a mediator of the antiviral response by inducing interferon (IFN) as well as...

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