Surfactant protein-D, a potential mediator of inflammation in axial spondyloarthritis.

doi:10.1093/rheumatology/key187

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Surfactant protein-D, a potential mediator of inflammation in axial spondyloarthritis.

Rheumatology (Oxford, England) - 1 Oct 2018

Munk Heidi L, Fakih Dalia, Christiansen Lene, Tan Qihua, Christensen Anne F, Ejstrup Leif, Loft Anne G, Junker Kirsten, Kyvik Kirsten O, Jounblat Rania, Holmskov Uffe, Sorensen Grith L, Junker Peter

Abstract excerpt

Objectives: Surfactant protein-D (SP-D), an innate immune defence molecule of the collectin family, is expressed in lungs and additional extrapulmonary epithelia. SP-D has immune modulatory and anti-microbial effects depending on its oligomerization. The ratio of high molecular weight (HMW): low molecular weight (LMW) SP-D in serum is mainly determined by the Met11Thr polymorphism (SNP rs721917). We aimed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Young Adult

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to HLA-B27 Antigen

Share to Inflammation Mediators

Share to Polymorphism, Single Nucleotide

Share to Protein Multimerization

Share to Pulmonary Surfactant-Associated Protein D

Share to Spondylarthritis

Source

Open in PubMed

Identifiers

PMID: 29982797
DOI: 10.1093/rheumatology/key187

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Surfactant protein-D, a potential mediator of inflammation in axial spondyloarthritis.PMID 29982797Read ↗

Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis.Semantic proximity Read ↗

Circulating surfactant protein D is decreased in early rheumatoid arthritis: a 1-year prospective study.Semantic proximity Read ↗

Circulating surfactant protein D is decreased in systemic lupus erythematosus.Semantic proximity Read ↗

Surfactant protein D multimerization and gene polymorphism in COPD and asthma.Semantic proximity Read ↗

Immunomodulatory roles of surfactant proteins A and D: implications in lung disease.Semantic proximity Read ↗

Association of Serum Surfactant Protein D and SFTPD gene variants with asthma in Danish children, adolescents and young adultsSemantic proximity Read ↗

Increased plasma concentration of surfactant protein D in chronic periodontitis independent of SFTPD genotype: potential role as a biomarker.Semantic proximity Read ↗

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury.Semantic proximity Read ↗

Association of serum surfactant protein D and SFTPD gene variants with asthma in Danish children, adolescents, and young adults.Semantic proximity Read ↗

Structure, genetics and function of the pulmonary associated surfactant proteins A and D: The extra-pulmonary role of these C type lectins.Semantic proximity Read ↗

Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.Semantic proximity Read ↗

Surfactant protein-D and pulmonary host defense.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.