Article
Giant Pediatric Rhabdoid Meningioma Associated with a Germline BAP1 Pathogenic Variation: A Rare Clinical Case.
World neurosurgery - 1 Nov 2018
Ravanpay Ali C, Barkley Ariana, White-Dzuro Gabrielle A, Cimino Patrick J, Gonzalez-Cuyar Luis F, Lockwood Christina, Halasz Lia M, Hisama Fuki M, Ferreira Manuel
Abstract excerpt
BACKGROUND: Rhabdoid meningiomas are rare World Health Organization grade 3 tumors that tend to follow an aggressive course, with an increased likelihood for local recurrence, remote metastasis, and cerebrospinal fluid dissemination. Genetic testing has found certain genes associated with reduced time to tumor recurrence. BAP1 (BRCA1-associated protein 1) is a tumor suppressor gene that is associated with...
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