Article
Clinical and Molecular Features of BAP1-Mutated Meningiomas: Case Series.
Molecular carcinogenesis - 1 Oct 2026
Pradilla Ivan, Alfattal Rasha, McGovern Susan L, Raza Shaan M, DeMonte Franco, Ballester Leomar Y, Patel Chirag B, Kamiya-Matsuoka Carlos
Abstract excerpt
BRCA1-associated protein 1 (BAP1)-deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely characterized. We report three cases of BAP1-deficient meningiomas...
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- Adult
- Female
- Humans
- Male
- Middle Aged
- Young Adult
- Germ-Line Mutation