Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of tumor necrosis factor alpha polymorphism TNF-α-238 (rs 361525) as a risk factor for development of acute kidney injury in critically ill patients.

Molecular biology reports - 1 Oct 2018

Fatani Sameer H, ALrefai Abeer Ahmed, Al-Amodi Hiba S, Kamel Hala F, Al-Khatieb Kasem, Bader Hamdy

Abstract excerpt

Critically ill patients revealed significant adverse outcomes (sepsis, septic shock, organ dysfunction/failure, and mortality) despite variable effort. AIM: this study evaluated the association of TNF-a-238 (rs 361525) with adverse outcomes in critically ill patients. TNF-α-238 (rs 361525) SNP was performed by RT-PCR on 200 critically-ill patients (112 had severe sepsis and septic shock and 88 were septic), 127...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylglucosaminidase
Share to Acute Kidney Injury

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Creatinine

Share to Critical Illness

Share to Genetic Association Studies

Share to Hospitalization

Share to Sepsis

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 29978383
DOI: 10.1007/s11033-018-4230-8

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of tumor necrosis factor alpha polymorphism TNF-α-238 (rs 361525) as a risk factor for development of acute kidney injury in critically ill patients.PMID 29978383Read ↗

Association of TNF-α-308 (G >A) (rs1800629) Gene Polymorphism with Adverse Outcomes of Sepsis in Critically Ill Patients.Semantic proximity Read ↗

The TNF-α (-238 G/A) polymorphism could protect against development of severe sepsis.Semantic proximity Read ↗

TNF -308G > a promoter polymorphism (rs1800629) and outcome from critical illness.Semantic proximity Read ↗

Tumor necrosis factor-α -308G/A and -238G/A polymorphisms are associated with increased risks of sepsis: evidence from an updated meta-analysis.Semantic proximity Read ↗

Evaluation of TNF-α genetic polymorphisms as predictors for sepsis susceptibility and progression.Semantic proximity Read ↗

Genetic variation in the TNF gene is associated with susceptibility to severe sepsis, but not with mortality.Semantic proximity Read ↗

Interleukin-10: Genetic and biochemical prediction of sepsis-induced acute kidney injury in critically ill patients in intensive care unit: A cross-sectional study.Semantic proximity Read ↗

Tumor necrosis factor gene polymorphism results in high TNF level in sepsis and septic shock.Semantic proximity Read ↗

Genetic predisposition to acute kidney injury induced by severe sepsis.Semantic proximity Read ↗

Role of Tumour Necrosis Factor-Alpha promoter 308A/G polymorphism in sepsis and sepsis mortality: A Meta-AnalysisSemantic proximity Read ↗

Tumour necrosis factor-α plus interleukin-10 low producer phenotype predicts acute kidney injury and death in intensive care unit patients.Semantic proximity Read ↗

Thrombomodulin gene polymorphism and the occurrence and prognostic value of sepsis acute kidney injury.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.