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Article

[Ineffective erythropoiesis in myelodysplastic syndrome].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2000

Iwama Atsushi

Abstract excerpt

Ineffective hematopoiesis is one of the hallmarks of myelodysplastic syndrome (MDS). Recently, several signaling pathways responsible for inefficient erythropoiesis in MDS have been uncovered. The p53-S100a8/S100a9-TLR4 pathway is involved in ineffective erythropoiesis in 5q minus (5q-) syndrome. Somatic mutations target multiple components of the messenger RNA (mRNA) splicing machinery including Splicing Factor...

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Source

Identifiers

PMID: 29973461
DOI: 10.11406/rinketsu.59.793

Genes

SRSF2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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