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Article

[Splicing factor mutations in myelodysplastic syndromes].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2000

Shiozawa Yusuke

Abstract excerpt

Splicing factor mutations represent a novel class of driver mutations in myelodysplastic syndromes, where four genes, including SF3B1, SRSF2, U2AF1, and ZRSR2, are most frequently affected. SF3B1 and SRSF2 mutations show prominent specificity to the syndrome subtypes characterized by increased ring sideroblasts and chronic myelomonocytic leukemia, respectively. These mutations are suspected to be involved in the...

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Source

Identifiers

PMID: 29877248
DOI: 10.11406/rinketsu.59.566

Genes

SRSF2
ZRSR2
ABCB7
PPOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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