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[Role of Aberrant Splicing in Pathogenesis of Myelodysplastic Syndromes-Review].

Zhongguo shi yan xue ye xue za zhi - 1 Apr 2017

Li Lin, Xiao Zhi-Jian, Sun Xue-Mei

Abstract excerpt

The spectrum of genetic abnormalities in myelodysplastic syndromes(MDS) has been revealed by high-throughput sequencing. However, the functional role of these mutations in occurrence and development of MDS was not delineated. The mutations in splicing factors have been identified as the commonest gene mutations in MDS. Recently, it was reported that the mutated or dysregulated splicing factors, including SF3B1,...

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Identifiers

PMID: 28446323
DOI: 10.7534/j.issn.1009-2137.2017.02.057

Genes

SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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