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Article

Senolytic drugs in respiratory medicine: is it an appropriate therapeutic approach?

Expert opinion on investigational drugs - 1 Jul 2018

Cazzola Mario, Matera Maria Gakriella, Rogliani Paola, Calzetta Luigino

Abstract excerpt

INTRODUCTION: Aging is the major risk factor for most of the chronic diseases. Cellular senescence is one of the main hallmarks of aging. A growing body of evidence implicates accelerated mechanisms of aging, including cellular senescence, in idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD) pathogenesis. Senolytics are pharmaceutical agents that eliminate senescent cells, thus...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29972333
DOI: 10.1080/13543784.2018.1492548

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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