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Article

Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis.

Biology of reproduction - 1 Dec 2018

Xiong Zhi, Wang Caixia, Wang Zilong, Dai Huaiqian, Song Qiancheng, Zou Zhipeng, Xiao Bo, Zhao Allen Zijian, Bai Xiaochun, Chen Zhenguo

Abstract excerpt

Sertoli cells (SCs) play a central role in testis development, and their normal number and functions are required for spermatogenesis. Although the canonical tuberous sclerosis complex-mammalian target of rapamycin complex 1(TSC-mTORC1) pathway is critical for testis development and spermatogenesis, the signaling mechanisms governing SC functions remain unclear. In this study, we generated two SC-specific mouse...

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Identifiers

PMID: 29961810
DOI: 10.1093/biolre/ioy144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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