Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse Testis

11 Sept 2015

Abstract excerpt

Maintenance of cell polarity is essential for Sertoli cell and blood-testis barrier (BTB) function and spermatogenesis; however, the signaling mechanisms that regulate the integrity of the cytoskeleton and polarity of Sertoli cells are not fully understood. Here, we demonstrate that rapamycin-insensitive component of target of rapamycin (TOR) (Rictor), a core component of mechanistic TOR complex 2 (mTORC2), was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Renal Diseases and Glomerulopathies
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26360620
DOI: 10.1210/en.2015-1217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse TestisPMID 26360620Read ↗

Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis.Semantic proximity Read ↗

A germline-specific role for the mTORC2 component Rictor in maintaining spermatogonial differentiation and intercellular adhesion in mouse testisSemantic proximity Read ↗

Inhibition of mTOR pathway decreases the expression of pre-meiotic and meiotic markers throughout postnatal development and in adult testes in miceSemantic proximity Read ↗

Mammalian target of rapamycin (mTOR): a central regulator of male fertility?Semantic proximity Read ↗

Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and SpermatogenesisSemantic proximity Read ↗

Cell-autonomous requirement for mammalian target of rapamycin (Mtor) in spermatogonial proliferation and differentiation in the mouse†Semantic proximity Read ↗

Retinoic Acid Induced Protein 14 ( Rai14 ) is dispensable for mouse spermatogenesisSemantic proximity Read ↗

Distribution and association of mTOR with its cofactors, raptor and rictor, in cumulus cells and oocytes during meiotic maturation in miceSemantic proximity Read ↗

Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-mediated Effects on mTORC1 and mTORC2Semantic proximity Read ↗

Depletion of Ric-8B leads to reduced mTORC2 activitySemantic proximity Read ↗

rpS6 Regulates Blood-Testis Barrier Dynamics Through Arp3-Mediated Actin Microfilament Organization in Rat Sertoli Cells. An In Vitro StudySemantic proximity Read ↗

Brahmi Ghrita Exerts Nephroprotective Effects by Restoring Cytoskeletal Integrity and Ion Transport in <i>Drosophila</i> Model of Polycystic Kidney DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.