Leveraging human-mouse studies to advance the genetics of hearing impairment in Africa.

Abstract excerpt

Mouse models are used extensively to understand human pathobiology and mechanistic functions of disease-associated loci. However, in this review, we investigate the potential of using genetic mouse models to identify genetic markers that can disrupt hearing thresholds in mice and then target the hearing-enriched orthologues and loci in humans. Currently, little is known about the real prevalence of genes that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Africa
• Share to Disease Models, Animal
• Share to Genetic Predisposition to Disease