Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Determinant of resistance to kanamycin in Streptomycin rimosus: amplification in the chromosome and reversible genetic instability].

Molekuliarnaia biologiia - 1 Jan 2000

Potekhin Ia A, Danilenko V N

Abstract excerpt

The study on the kanamycin resistance determinant (Kanr) in an oxytetracycline--producing strain of S. rimosus showed that it was capable of amplifying in the chromosome during selection for increasing the antibiotic resistance level. The amplification of the DNA fragment with a molecular weight of 10.3 MDa containing Kanr amounted to 300 copies per genome, which resulted in a more than 1000-fold increase in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Cloning, Molecular
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to Electrophoresis, Polyacrylamide Gel

Share to Phenotype

Share to Plasmids

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 2993855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Determinant of resistance to kanamycin in Streptomycin rimosus: amplification in the chromosome and reversible genetic instability].PMID 2993855Read ↗

[Analysis of genome rearrangements in Streptomyces kanamyceticus mutants].Semantic proximity Read ↗

[Isolation and study of the properties of Streptomyces kanamyceticus mutants with disorders of kanamycin biosynthesis].Semantic proximity Read ↗

[Structural changes in the composition of amplifying sequence AUD-Sr1 of Streptomyces rimosus after cloning into Escherichia coli].Semantic proximity Read ↗

The 387 kb linear plasmid pPZG101 of Streptomyces rimosus and its interactions with the chromosome.Semantic proximity Read ↗

[Genetic instability of the feature of streptomycin resistance in Streptomyces erythraeus].Semantic proximity Read ↗

[Hyperrecombination of plasmids is characteristic for hyperresistant strains of Escherichia coli].Semantic proximity Read ↗

Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus.Semantic proximity Read ↗

[TRANSDUCTION OF STREPTOMYCIN RESISTANCE IN RELATION TO STUDY OF THE STATE OF HETEROGENICITY IN ACTINOMYCETES].Semantic proximity Read ↗

[Superinfective proteins of Escherichia coli phage T4B and the pleiotropic effect of the rl mutation].Semantic proximity Read ↗

Gamma-butyrolactone-dependent expression of the Streptomyces antibiotic regulatory protein gene srrY plays a central role in the regulatory cascade leading to lankacidin and lankamycin production in Streptomyces rochei.Semantic proximity Read ↗

[Thermosensitive vector derived from RP1 plasmid for detection of transposable elements].Semantic proximity Read ↗

[Transposition of the composite synthetic transposon TnV (Tn5-Rep(pSC101)) is accompanied by the formation of the mini-plasmid pTnV, containing defective Is50-elements].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.