Article
Relationship of metabolic syndrome and its components with -844 G/A and HindIII C/G PAI-1 gene polymorphisms in Mexican children.
BMC pediatrics - 29 Mar 2012
De la Cruz-Mosso Ulises, Muñoz-Valle José F, Salgado-Goytia Lorenzo, García-Carreón Adrián, Illades-Aguiar Berenice, Castañeda-Saucedo Eduardo, Parra-Rojas Isela
Abstract excerpt
BACKGROUND: Several association studies have shown that -844 G/A and HindIII C/G PAI-1 polymorphisms are related with increase of PAI-1 levels, obesity, insulin resistance, glucose intolerance, hypertension and dyslipidemia, which are components of metabolic syndrome. The aim of this study was to analyze the allele and genotype frequencies of these polymorphisms in PAI-1 gene and its association with metabolic...
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