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Article

Disparate genomic characteristics of concurrent endometrial adenocarcinoma and ovarian granulosa cell tumor, revealed by targeted next-generation sequencing.

Pathology, research and practice - 1 Aug 2018

Choi Youn Jin, Ho Jungyoon, Lee Ahwon, Hur Soo Young, Park Hyeon-Chun, Park Jong Sup, Chung Yeun-Jun, Lee Sug Hyung

Abstract excerpt

Concurrence of both endometrial adenocarcinoma and ovarian adult granulosa cell tumor (aGCT) is believed to be related to high estrogen milieu, but genomic alterations of the concurrent endometrial adenocarcinoma and aGCT are not known. For this, we analyzed an uterine endometrial adenocarcinoma and an ovarian aGCT in a same patient by a targeted next generation sequencing (NGS). We found a germline mutation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29937308
DOI: 10.1016/j.prp.2018.06.009

Genes

FGFR2
FOXL2
STK11

Provenance

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