Aggressive Course of STK11/ FOXL2 -Wildtype Adult Granulosa Cell Tumor in Peutz– Jeghers Syndrome: A Case Report

Abstract excerpt

<title>Abstract</title> <p> Background: Peutz–Jeghers syndrome (PJS) predisposes to various neoplasms, including ovarian sex cord–stromal tumours. Adult granulosa cell tumour (AGCT) is a rare subtype, and bilateral advanced‑stage AGCT arising in PJS with negative <italic>STK11</italic> and <italic>FOXL2</italic> mutations is exceptionally rare. Case presentation: A 30‑year‑old woman with PJS was diagnosed wi...

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• Boston
• British Columbia
• CDC2 Protein Kinase
• Class Ia Phosphatidylinositol 3-Kinase
• Europe
• Forkhead Box Protein L2
• Granulosa Cell Tumor
• Whole Genome Sequencing

Identifiers and source

Literature Corpus work

5fbd0ffa-7ab6-5f70-b6ee-c82d2ba4a4ec

DOI

10.21203/rs.3.rs-9454998/v1