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Alzheimer’s disease master regulators analysis: search for potential molecular targets and drug repositioning candidates

23 Jun 2018

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a multifactorial and complex neuropathology that involves impairment of many intricate molecular mechanisms. Despite recent advances, AD pathophysiological characterization remains incomplete, which hampers the development of effective treatments. In fact, currently, there are no effective pharmacological treatments for AD. Integrative strategies such as transcription...

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PMID: 29935546
DOI: 10.1186/s13195-018-0394-7

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