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Article

Systematic analysis of biological roles of charged amino acid residues located throughout the structured inner wall of a virus capsid.

Scientific reports - 22 Jun 2018

Carrillo Pablo J P, Hervás Marta, Rodríguez-Huete Alicia, Pérez Rebeca, Mateu Mauricio G

Abstract excerpt

Structure-based mutational analysis of viruses is providing many insights into the relationship between structure and biological function of macromolecular complexes. We have systematically investigated the individual biological roles of charged residues located throughout the structured capsid inner wall (outside disordered peptide segments) of a model spherical virus, the minute virus of mice (MVM). The...

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Identifiers

PMID: 29934575
DOI: 10.1038/s41598-018-27749-8
PMCID: PMC6015035

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