Article
Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations.
Scientific reports - 22 Jun 2017
Guerra Pablo, Valbuena Alejandro, Querol-Audí Jordi, Silva Cristina, Castellanos Milagros, Rodríguez-Huete Alicia, Garriga Damià, Mateu Mauricio G, Verdaguer Nuria
Abstract excerpt
Recent studies reveal that the mechanical properties of virus particles may have been shaped by evolution to facilitate virus survival. Manipulation of the mechanical behavior of virus capsids is leading to a better understanding of viral infection, and to the development of virus-based nanoparticles with improved mechanical properties for nanotechnological applications. In the minute virus of mice (MVM),...
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