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Article

A slender tract of glycine residues is required for translocation of the VP2 protein N-terminal domain through the parvovirus MVM capsid channel to initiate infection.

The Biochemical journal - 1 Oct 2013

Castellanos Milagros, Pérez Rebeca, Rodríguez-Huete Alicia, Grueso Esther, Almendral José M, Mateu Mauricio G

Abstract excerpt

Viruses constitute paradigms to study conformational dynamics in biomacromolecular assemblies. Infection by the parvovirus MVM (minute virus of mice) requires a conformational rearrangement that involves the intracellular externalization through capsid channels of the 2Nt (N-terminal region of VP2). We have investigated the role in this process of conserved glycine residues in an extended glycine-rich tract...

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Source

Identifiers

PMID: 23875612
DOI: 10.1042/BJ20130503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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