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Article

Manipulation of the mechanical properties of a virus by protein engineering.

Proceedings of the National Academy of Sciences of the United States of America - 18 Mar 2008

Carrasco Carolina, Castellanos Milagros, de Pablo Pedro J, Mateu Mauricio G

Abstract excerpt

In a previous study, we showed that the DNA molecule within a spherical virus (the minute virus of mice) plays an architectural role by anisotropically increasing the mechanical stiffness of the virus. A finite element model predicted that this mechanical reinforcement is a consequence of the interaction between crystallographically visible, short DNA patches and the inner capsid wall. We have now tested this...

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Identifiers

PMID: 18334651
DOI: 10.1073/pnas.0708017105
PMCID: PMC2393779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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