Article
Genomic convergence of locus-based GWAS meta-analysis identifies AXIN1 as a novel Parkinson's gene.
Immunogenetics - 1 Sept 2018
Saeed Mohammad
Abstract excerpt
Parkinson's disease (PD) is a common, disabling neurodegenerative disorder with significant genetic underpinnings. Multiple genome-wide association studies (GWAS) have been conducted with identification of several PD loci. However, these only explain about 25% of PD genetic risk indicating that additional loci of modest effect remain to be discovered. Association clustering methods such as gene-based tests are...
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