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Article

Defective NaCl Reabsorption in Salivary Glands of Eda-Null X-LHED Mice.

Journal of dental research - 1 Oct 2018

Mukaibo T, Munemasa T, Masaki C, Cui C Y, Melvin J E

Abstract excerpt

Mutations in the ectodysplasin A gene ( EDA) cause X-LHED (X-linked hypohidrotic ectodermal dysplasia), the most common human form of ectodermal dysplasia. Defective EDA signaling is linked to hypoplastic development of epithelial tissues, resulting in hypotrichosis, hypodontia, hypohidrosis, and xerostomia. The primary objective of the present study was to better understand the salivary gland dysfunction...

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Share to Ectodermal Dysplasia 1, Anhidrotic
Share to Ectodysplasins
Share to Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymerase Chain Reaction

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Source

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Identifiers

PMID: 29913094
DOI: 10.1177/0022034518782461
PMCID: PMC6151911

Genes

EDA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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