Article
Primary Melanoma Histologic Subtype: Impact on Survival and Response to Therapy.
Journal of the National Cancer Institute - 1 Feb 2019
Lattanzi Michael, Lee Yesung, Simpson Danny, Moran Una, Darvishian Farbod, Kim Randie H, Hernando Eva, Polsky David, Hanniford Doug, Shapiro Richard, Berman Russell, Pavlick Anna C, Wilson Melissa A, Kirchhoff Tomas, Weber Jeffrey S, Zhong Judy, Osman Iman
Abstract excerpt
BACKGROUND: Two primary histologic subtypes, superficial spreading melanoma (SSM) and nodular melanoma (NM), comprise the majority of all cutaneous melanomas. NM is associated with worse outcomes, which have been attributed to increased thickness at presentation, and it is widely expected that NM and SSM would exhibit similar behavior once metastasized. Herein, we tested the hypothesis that primary histologic...
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