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Article

Role of tumor-associated macrophages at the invasive front in human colorectal cancer progression.

Cancer science - 1 Jul 2021

Inagaki Katsuaki, Kunisho Shoma, Takigawa Hidehiko, Yuge Ryo, Oka Shiro, Tanaka Shinji, Shimamoto Fumio, Chayama Kazuaki, Kitadai Yasuhiko

Abstract excerpt

Macrophages are an essential component of antitumor activity; however, the role of tumor-associated macrophages (TAMs) in colorectal cancer (CRC) remains controversial. Here, we elucidated the role of TAMs in CRC progression, especially at the early stage. We assessed the TAM number, phenotype, and distribution in 53 patients with colorectal neoplasia, including intramucosal neoplasia, submucosal invasive...

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Share to Antigens, Differentiation, Myelomonocytic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33964093
DOI: 10.1111/cas.14940
PMCID: PMC8253270

Genes

CD163
CD68

Provenance

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