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Article

Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer.

Oncotarget - 6 Dec 2016

Kwak Yoonjin, Koh Jiwon, Kim Duck-Woo, Kang Sung-Bum, Kim Woo Ho, Lee Hye Seung

Abstract excerpt

BACKGROUND: The immunoscore (IS), an index based on the density of CD3+ and CD8+ tumor-infiltrating lymphocytes (TILs) in the tumor center (CT) and invasive margin (IM), has gained considerable attention as a prognostic marker. Tumor-associated macrophages (TAMs) have also been reported to have prognostic value. However, its clinical significance has not been fully clarified in patients with advanced CRC who...

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Share to Antigens, Differentiation, Myelomonocytic
Share to CD163 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD3 Complex

Share to CD8-Positive T-Lymphocytes

Share to Class I Phosphatidylinositol 3-Kinases

Share to Lymphocyte Count

Share to Lymphocytes, Tumor-Infiltrating

Share to Proportional Hazards Models

Source

Open in PubMed Open full text

Identifiers

PMID: 27835889
DOI: 10.18632/oncotarget.13207
PMCID: PMC5348429

Genes

KRAS
FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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