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Article

CRISPR therapeutic tools for complex genetic disorders and cancer (Review).

International journal of oncology - 1 Aug 2018

Baliou Stella, Adamaki Maria, Kyriakopoulos Anthony M, Spandidos Demetrios A, Panayiotidis Mihalis, Christodoulou Ioannis, Zoumpourlis Vassilis

Abstract excerpt

One of the fundamental discoveries in the field of biology is the ability to modulate the genome and to monitor the functional outputs derived from genomic alterations. In order to unravel new therapeutic options, scientists had initially focused on inducing genetic alterations in primary cells,...

Topics

Animals
CRISPR-Cas Systems
Cell Line, Tumor
Gene Editing
Genetic Predisposition to Disease
Genetic Therapy
Humans
Mice
Neoplasms
Precision Medicine

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29901119
DOI: 10.3892/ijo.2018.4434
PMCID: PMC6017271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-29901119-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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