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CRISPR based therapeutics: a new paradigm in cancer precision medicine

25 Mar 2022

Abstract excerpt

BACKGROUND: Clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated protein (Cas) systems are the latest addition to the plethora of gene-editing tools. These systems have been repurposed from their natural counterparts by means of both guide RNA and Cas nuclease engineering. These RNA-guided systems offer greater programmability and multiplexing capacity than previous generation gene...

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PMID: 35337340
DOI: 10.1186/s12943-022-01552-6

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