Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative proteomic analysis identifies proteins and pathways related to neuronal development in differentiated SH-SY5Y neuroblastoma cells

23 Jun 2017

Abstract excerpt

SH-SY5Y neuroblastoma cells are susceptible to differentiation using retinoic acid (RA) and brain-derived neurotrophic factor (BDNF), providing a model of neuronal differentiation. We compared SH-SY5Y cells proteome before and after RA/BDNF treatment using iTRAQ and phosphopeptide enrichment strategies. We identified 5587 proteins, 366 of them with differential abundance. Differentiated cells expressed proteins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neuroblastoma Research and Treatments
Share to Protein Degradation and Inhibitors
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29900121
DOI: 10.1016/j.euprot.2017.06.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative proteomic analysis identifies proteins and pathways related to neuronal development in differentiated SH-SY5Y neuroblastoma cellsPMID 29900121Read ↗

Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5YSemantic proximity Read ↗

Quantitative profiling of axonal guidance proteins during the differentiation of human neurospheresSemantic proximity Read ↗

Neuronal Differentiation of LUHMES Cells Induces Substantial Changes of the ProteomeSemantic proximity Read ↗

Transcriptome-wide alternative mRNA splicing analysis reveals post-transcriptional regulation of neuronal differentiationSemantic proximity Read ↗

Expression and Localization of AβPP in SH-SY5Y Cells Depends on Differentiation StateSemantic proximity Read ↗

Phenotyping of tianma-stimulated differentiated rat neuronal b104 cells by quantitative proteomics.Semantic proximity Read ↗

Methods used to achieve different levels of the neuronal differentiation process in SH‐SY5Y and Neuro2a cell lines: An integrative reviewSemantic proximity Read ↗

Cross-Pipeline RNA-seq Analysis Reveals Core Regulatory Gene Signatures Driving P19 Cell NeurogenesisSemantic proximity Read ↗

Deciphering the protein dynamics and molecular determinants of iPSC-derived neuronsSemantic proximity Read ↗

Quantitative Phosphoproteomic Analysis Identifies Activation of the RET and IGF-1R/IR Signaling Pathways in NeuroblastomaSemantic proximity Read ↗

Temporal dynamics of proteome and phosphorproteome during neuronal differentiation in the reference KOLF2.1J iPSC lineSemantic proximity Read ↗

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.