Article
Frequent and Rare HABP2 Variants Are Not Associated with Increased Susceptibility to Familial Nonmedullary Thyroid Carcinoma in the Spanish Population.
Hormone research in paediatrics - 1 Jan 2018
de Randamie Rajdee, Martos-Moreno Gabriel Ángel, Lumbreras César, Chueca Maria, Donnay Sergio, Luque Manuel, Regojo Rita María, Mendiola Marta, Hardisson David, Argente Jesús, Moreno José C
Abstract excerpt
BACKGROUND/AIMS: A genomic HABP2 variant was proposed to be responsible for familial nonmedullary thyroid carcinoma (FNMTC). However, its involvement has been questioned in subsequent studies. We aimed to identify genetic HABP2 mutations in a series of FNMTC patients and investigate their involvement in the disease. METHODS: HABP2 was sequenced from 6 index patients. Presence of the variants was investigated in...
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