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Article

HABP2 germline variants are uncommon in familial nonmedullary thyroid cancer.

BMC medical genetics - 17 Aug 2016

Weeks Alexia L, Wilson Scott G, Ward Lynley, Goldblatt Jack, Hui Jennie, Walsh John P

Abstract excerpt

BACKGROUND: The genetic basis of nonsyndromic familial nonmedullary thyroid cancer (FNMTC) is poorly understood. A recent study identified HABP2 as a tumor suppressor gene and identified a germline variant (G534E) in an extended FNMTC kindred. The relevance of this to other FNMTC kindreds is uncertain. METHODS: Sanger sequencing was performed on peripheral blood DNA from probands from 37 Australian FNMTC kindreds...

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Source

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Identifiers

PMID: 27530615
DOI: 10.1186/s12881-016-0323-1
PMCID: PMC4988026

Genes

HABP2
FOXE1
SRGAP1
SRRM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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