Article
Predictive polymorphisms for breast cancer in postmenopausal Mexican women.
Journal of cancer research and therapeutics - 1 Jan 2000
Sierra-Martinez Mónica, Hernández-Cadena Leticia, García-Sánchez José Rubén, Acosta-Altamirano Gustavo, Palacios-Reyes Carmen, Alonso-Themann Patricia García, García-Ortiz Liliana, Quintas-Granados Laura Itzel, Reyes-Hernández Octavio Daniel
Abstract excerpt
CONTEXT: Several factors contribute to the increase in breast cancer (BC) incidence, such as lifetime exposure to estrogen, early menarche and older ages at first birth, menopause, and the increased prevalence of postmenopausal obesity. In fact, there is an association between an increased BC risk and elevated estrogen levels, which may be involved in carcinogenesis via the estrogen receptor alpha (ERα) encoded...
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