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Article

Estrogen receptor alpha (ERS1) SNPs c454-397T>C (PvuII) and c454-351A>G (XbaI) are risk biomarkers for breast cancer development.

Molecular biology reports - 1 Aug 2014

Madeira Klesia Pirola, Daltoé Renata Dalmaschio, Sirtoli Gabriela Modenesi, Carvalho Alex Assis, Rangel Leticia Batista Azevedo, Silva Ian Victor

Abstract excerpt

There are several risk factors related to Breast Cancer (BC) risks and response to chemotherapy with SERMs. Recently some single nucleotide polymorphisms (SNPs) on ESR1 gene have been associated to this disease. However, data are still inconclusive. The present study aimed to investigate the association of SNPs c454-397T>C (also called PvuII) and c454-351A>G (so called XbaI) to incidence of sporadic BC; ERα...

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Identifiers

PMID: 24928087
DOI: 10.1007/s11033-014-3419-8

Genes

ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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