Article
Polygenic differential susceptibility to cumulative stress exposure and childhood obesity.
International journal of obesity (2005) - 1 Jun 2018
Sun Ying, Fang Jiao, Wan Yuhui, Hu Jingjing, Xu Yuanyuan, Tao Fangbiao
Abstract excerpt
OBJECTIVE: To examine whether polygenic susceptibility for body mass index (BMI) interacts with cumulative stress exposure, potentially exacerbating and buffering the effects of chronic stress, to predict obesity during childhood. METHODS: Data were analyzed from an established prospective puberty cohort in Anhui province, China. A total of 1000 children (421 boys and 579 girls, mean (standard deviation) age 8.97...
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