Article
Impacts of WNT1-inducible signaling pathway protein 1 polymorphism on hepatocellular carcinoma development.
PloS one - 1 Jan 2018
Chen Chih-Tien, Lee Hsiang-Lin, Chiou Hui-Ling, Chou Chia-Hsuan, Wang Po-Hui, Yang Shun-Fa, Chou Ying-Erh
Abstract excerpt
BACKGROUND: WNT1-inducible signaling pathway protein 1 (WISP1) is a member of CCN protein family and a downstream target of β-catenin. Aberrant WISP1 expression is associated with carcinogenesis. In the current study, we focused on examining WISP1 single nucleotide polymorphisms (SNPs) to elucidate hepatocellular carcinoma (HCC) clinicopathologic characteristics. METHODOLOGY/PRINCIPAL FINDINGS: The WISP1 SNPs...
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