Article
WISP1 genetic variants as predictors of tumor development with urothelial cell carcinoma.
Urologic oncology - 1 Apr 2018
Lee Hsiang-Lin, Chiou Hui-Ling, Wang Shian-Shiang, Hung Sheng-Chun, Chou Ming-Chih, Yang Shun-Fa, Hsieh Ming-Ju, Chou Ying-Erh
Abstract excerpt
OBJECTIVES: Urothelial cell carcinoma (UCC) of the urinary bladder is a major malignancy of the genitourinary tract. Etiological factors, such as the environment, ethnicity, genetics, and diet, contribute to UCC carcinogenesis. WNT1-inducible signaling pathway protein 1 (WISP1), also known as CCN4, a cysteine-rich protein belonging to the Cyr61, CTGF, Nov (CCN) family of matricellular proteins, has many...
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