Article
Expression and regulation of the Pseudomonas aeruginosa hibernation promoting factor.
Molecular microbiology - 1 Oct 2018
Akiyama Tatsuya, Williamson Kerry S, Franklin Michael J
Abstract excerpt
Bacterial biofilms contain subpopulations of cells that are dormant and highly tolerant to antibiotics. While dormant, the bacteria must maintain the integrity of macromolecules required for resuscitation. Previously, we showed that hibernation promoting factor (HPF) is essential for protecting Pseudomonas aeruginosa from ribosomal loss during dormancy. In this study, we mapped the genetic components required for...
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