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Article

Ribosome hibernation factor promotes Staphylococcal survival and differentially represses translation.

Nucleic acids research - 2 Jun 2016

Basu Arnab, Yap Mee-Ngan F

Abstract excerpt

In opportunistic Gram-positive Staphylococcus aureus, a small protein called hibernation-promoting factor (HPFSa) is sufficient to dimerize 2.5-MDa 70S ribosomes into a translationally inactive 100S complex. Although the 100S dimer is observed in only the stationary phase in Gram-negative gammaproteobacteria, it is ubiquitous throughout all growth phases in S. aureus The biological significance of the 100S...

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Identifiers

PMID: 27001516
DOI: 10.1093/nar/gkw180
PMCID: PMC4889938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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