Article
A Variable Polyglutamine Repeat Affects Subcellular Localization and Regulatory Activity of a Populus ANGUSTIFOLIA Protein.
G3 (Bethesda, Md.) - 31 Jul 2018
Bryan Anthony C, Zhang Jin, Guo Jianjun, Ranjan Priya, Singan Vasanth, Barry Kerrie, Schmutz Jeremy, Weighill Deborah, Jacobson Daniel, Jawdy Sara, Tuskan Gerald A, Chen Jin-Gui, Muchero Wellington
Abstract excerpt
Polyglutamine (polyQ) stretches have been reported to occur in proteins across many organisms including animals, fungi and plants. Expansion of these repeats has attracted much attention due their associations with numerous human diseases including Huntington's and other neurological maladies. This suggests that the relative length of polyQ stretches is an important modulator of their function. Here, we report...
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