Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory complexes.

BMC genomics - 23 Nov 2010

Whan Vicki, Hobbs Matthew, McWilliam Sean, Lynn David J, Lutzow Ylva Strandberg, Khatkar Mehar, Barendse William, Raadsma Herman, Tellam Ross L

Abstract excerpt

BACKGROUND: About forty human diseases are caused by repeat instability mutations. A distinct subset of these diseases is the result of extreme expansions of polymorphic trinucleotide repeats; typically CAG repeats encoding poly-glutamine (poly-Q) tracts in proteins. Polymorphic repeat length variation is also apparent in human poly-Q encoding genes from normal individuals. As these coding sequence repeats are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome

Share to Peptides

Share to Proteins

Share to RNA Splicing

Share to Transcription, Genetic

Share to Trinucleotide Repeats

Source

Open in PubMed Open full text

Identifiers

PMID: 21092319
DOI: 10.1186/1471-2164-11-654
PMCID: PMC3014979

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory complexes.PMID 21092319Read ↗

Genome variants associated with RNA splicing variations in bovine are extensively shared between tissues.Semantic proximity Read ↗

Integrative analysis of quantitative trait loci of alternative polyadenylation and GWAS highlights key regulators of milk production and immune traits in Holstein.Semantic proximity Read ↗

The structural plasticity of polyglutamine repeatsSemantic proximity Read ↗

Common polymorphic transcript variation in human disease.Semantic proximity Read ↗

An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.Semantic proximity Read ↗

Juvenile Huntington’s Disease and Other PolyQ Diseases, Update on Neurodevelopmental Character and Comparative Bioinformatic Review of Transcriptomic and Proteomic DataSemantic proximity Read ↗

Juvenile Huntington’s Disease and Other PolyQ diseases, Update on Neurodevelopmental Character and Comparative Bioinformatic Review of Transcriptomic DataSemantic proximity Read ↗

The expanding role for chromatin and transcription in polyglutamine disease.Semantic proximity Read ↗

Structural variants and short tandem repeats impact gene expression and splicing in bovine testis tissue.Semantic proximity Read ↗

Somatic instability of the DNA sequences encoding the polymorphic polyglutamine tract of the AIB1 gene.Semantic proximity Read ↗

Putative bovine topological association domains and CTCF binding motifs can reduce the search space for causative regulatory variants of complex traitsSemantic proximity Read ↗

CAG-encoded polyglutamine length polymorphism in the human genomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.