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Article

SLC12A7 alters adrenocortical carcinoma cell adhesion properties to promote an aggressive invasive behavior

8 Jun 2018

Abstract excerpt

BACKGROUND: Altered expression of Solute Carrier Family 12 Member 7 (SLC12A7) is implicated to promote malignant behavior in multiple cancer types through an incompletely understood mechanism. Recent studies have shown recurrent gene amplifications and overexpression of SLC12A7 in adrenocortical carcinoma (ACC). The potential mechanistic effect(s) of SLC12A7 amplifications in portending an aggressive behavior in...

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PMID: 29884238
DOI: 10.1186/s12964-018-0243-0

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