Article

Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma

2025-04-07

Abstract excerpt

Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy with high mortality and poor prognosis. To elucidate the genetic underpinnings of ACCs, we have analyzed the transcriptome data of 112 ACC tumor samples from patients enrolled in the TCGA and NCI. Among 72 bimodally expressed genes stratifying patients into prognostic groups, we focused on SEMA7A , as it encodes a glycosylphosphatidylino...

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Literature Corpus work: 143e2e91-f285-59a2-ac1e-c818622fa59a
DOI: 10.1101/2025.04.03.647086

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