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Article

"Gap hunting" to characterize clustered probe signals in Illumina methylation array data.

Epigenetics & chromatin - 1 Jan 2016

Andrews Shan V, Ladd-Acosta Christine, Feinberg Andrew P, Hansen Kasper D, Fallin M Daniele

Abstract excerpt

BACKGROUND: The Illumina 450k array has been widely used in epigenetic association studies. Current quality-control (QC) pipelines typically remove certain sets of probes, such as those containing a SNP or with multiple mapping locations. An additional set of potentially problematic probes are those with DNA methylation distributions characterized by two or more distinct clusters separated by gaps. Data-driven...

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PMID: 27980682
DOI: 10.1186/s13072-016-0107-z
PMCID: PMC5142147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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