Article

Genetic Spectrum and Lipid Profiles of 46 Chinese Children With Dyslipidemia Analyzed by Whole-Exome Sequencing: A 10-Year Single-Center Retrospective Study

2025-12-01

Abstract excerpt

<title>Abstract</title> <p> Objective To characterize the genetic spectrum and lipid phenotypes of Chinese children with dyslipidemia using whole-exome sequencing (WES) and to explore genotype–phenotype correlations. Methods We retrospectively analyzed 46 children with dyslipidemia who underwent WES at Shanghai Children’s Medical Center between June 2015 and September 2025. Clinical characteristics, seven lipid...

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Literature Corpus work: 497b6fd4-0ffb-5fa1-a414-ac9f0dd69b60
DOI: 10.21203/rs.3.rs-8078709/v1

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